"S.H.I.E.L.D. #1" is the tale of the organization's origins, which include Leonardo Da Vinci, Issac Newton, and all sorts of other historical figures who were as close to being superheroes as possible. Also, it's written by Jonathan Hickman and drawn by Dustin Weaver, and as you can see, he does a face-melting job.
Here is the solicitation from Marvel's website for the book, on sale today. After you read this, leave immediately and go buy it.
"Leonardo Da Vinci was an agent of S.H.I.E.L.D. So was Issac Newton. So were Imhotep and Zhang Heng and Galileo and many other geniuses throughout time. They were the first heroes to defeat Galactus and the Brood and turn Celestials back. They saved the world long before Captain America or Iron Man were ever born, but what does this mean to our heroes of today? What does this mean to Nick Fury? Do not miss this Marvel Comics masterpiece that fans will be talking about for decades to come."